"sitting in the orchard, eating an apple and sipping tea, his relaxed posture." This is the attitude of a Lord

Dude get terminal cancer and now live his last days on the countryside farm. Get power from a dying alien queen that let him evolve any carbon-creature but he has no blueprint and have to do with trial and erro, with the use of knowleged to know how to build better creatures. They more or less divided between Magic creatures and Technological creatures. So he decided to turn they smaller than ant size and observe

then play on his farm and evolve their genes and civilization, while he do minimal intervention. This will evolve into a variety of civilizations, well-incorporated tropes and increasing powerlvls, with later emplying the help of the world to make their own gene creatures as if was a game.

• The MC personality is the greatest problem, he is almost useless story-wise, because he spend 90% of the story just watching things unfold and so the story shift to following the evolved creatures and players that are teleported to the world. Sadly most players like the MC also are of the opinion of hidenly build up before exploding with power, however they are far more interesting than the MC himself because they are alot more invested on the world.
• The players, the sand-box characters and later aliens, seen to lack any type of sense of doubt when is related to the MC bullsh*t and will gladly twist and do logic leaps to make the MC words make sense to reality that can get weird, and I just put on the "setting logic" category of suspension of disbelief.
• The sandbox characters lack of proper development, because the very nature of the story you only see the most important moments of the world and characters and they may feel one dimensional at times. Despise they being good characters overall that seen to lack screen time to show how they are and are still able to pull incredible and emotional feats.
• (that may be my own weird vision) Weirdly treatment of the Male Leads compared to the female leads. And not because there is a specific lack of Male Main character, as the author do more or less 1 arc for each gender to lead, but when I find weird some tropes that the male characters suffer that don't seen to happen. Males for a time are s*x s*aves to powerful witchs, Male player is almost used as s*x toy because his slime race, the male player go to a planet and is forced to turn into a girl, male players are forced to breed children (by kissing), male player are captured by pixel raider and r*ped (but is just magic transfer). I guess is comedic, but always struck me as odd

Don't take the small size fool you, the story has more good points than bad, but I find easy to point the things that bothered me.

This must be one of the best Sandbox/god-game themed story, that lead to incredible mix and match of eastern and western ideas of Fantasy that is well grounded on the rules of the setting. Meanwhile the sandbox characters despise their brief moments seen lived with their own ideas and agenda, and aren't just generic NPCs. While the new powers and evolutions seen to be organic grown from the previous setup and aren't just arbitarry given to the system after a "lvl up". This is a very "organic" story in more sense than one.